clinical-application

TAVR (Transcatheter Aortic Valve Replacement)

Catheter-based replacement of the aortic valve in patients with severe aortic stenosis. One of the largest changes in cardiovascular medicine over the past decade — TAVR has steadily expanded from high-risk-only (PARTNER 1, 2010) to intermediate-risk (PARTNER 2, 2016) and now low-surgical-risk indications (PARTNER 3 / Evolut Low Risk, 2019). Two valve platforms dominate: balloon-expandable Edwards SAPIEN and self-expanding Medtronic Evolut.

Clinical workflow

  1. Pre-procedure CT — contrast-enhanced ECG-gated cardiac CT measures aortic annulus, coronary heights, access vessels (iliofemoral runoff). Dedicated 64-slice-class CT essential; cardiac + peripheral runoff in one exam.
  2. Heart Team evaluation — interventional cardiology + cardiothoracic surgery + cardiac imaging + anesthesia review pre-procedure.
  3. Access — transfemoral default (>95% of cases); alternative access (transcaval, transapical, transaortic, subclavian, carotid) less frequent.
  4. Valve deployment — balloon-expandable (Edwards SAPIEN 3 / Ultra) or self-expanding (Medtronic Evolut PRO+ / FX) under fluoroscopic + TEE guidance.
  5. Post-deployment assessment — paravalvular leak evaluation, hemodynamics, coronary patency, final angiography.

Typical imaging systems

Cardiac CT (pre-procedure):

Fluoroscopy (procedure) — biplane cath lab or hybrid OR:

TEE (procedure):

Room requirements

Hybrid OR or biplane cath lab. Sterile OR-grade environment with full cath-lab imaging capability. Perfusion team, anesthesiology, cardiothoracic backup, TEE, hemodynamics. Multi-disciplinary Heart Team evaluation before every case.

Procedure characteristics

Equipment considerations that bite

Operational reality

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