clinical-application

TAVR (Transcatheter Aortic Valve Replacement)

Catheter-based replacement of the aortic valve in patients with severe aortic stenosis who are poor candidates for open surgical AVR. One of the largest changes in cardiovascular medicine over the past decade — TAVR has steadily expanded from high-risk to intermediate- and now low-risk indications.

Clinical workflow

  1. Pre-procedure CT — contrast-enhanced ECG-gated cardiac CT measures aortic annulus, coronary heights, access vessels. Dedicated 64-slice-class CT essential; cardiac + peripheral runoff in one exam.
  2. Access — transfemoral default; alternative access (TA, TAo, subclavian, carotid) less frequent.
  3. Valve deployment — balloon-expandable (Edwards SAPIEN) or self-expanding (Medtronic Evolut) under fluoroscopic + TEE guidance.
  4. Post-deployment assessment — paravalvular leak evaluation, hemodynamics, final angiography.

Typical imaging systems

Room requirements

Hybrid OR or biplane cath lab. Sterile OR-grade environment with full cath lab imaging capability. Perfusion team, anesthesiology, cardiothoracic backup, TEE, hemodynamics. Multi-disciplinary heart team evaluation before every case.

Procedure characteristics

Imaging quality matters

Small annulus measurement errors (~1 mm) change valve sizing decisions. CT protocol standardization + reader experience affect outcomes. Procedural dose varies widely — complex cases can push regulatory limits.

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